Inhibitors | Comment | Organism | Structure |
---|---|---|---|
4,6-dihydroxy-5-methoxy-6a-methylcyclohexa[de]indano-[7,6-e]cyclopenta[c]2H-pyran-1,9-dione | TAEMC161, specific inhibitor | Aspergillus parasiticus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Aspergillus parasiticus | 5829 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Aspergillus parasiticus | - |
- |
- |
Aspergillus parasiticus NIAH-26 | - |
- |
- |
Purification (Comment) | Organism |
---|---|
ammonium sulfate precipitation, butyl-Toyopearl 650 M column chromatography | Aspergillus parasiticus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
mycelium | - |
Aspergillus parasiticus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(1'S,5'S)-hydroxyaverantin + NAD+ | - |
Aspergillus parasiticus | 5'-oxoaverantin + NADH + H+ | - |
? | |
(1'S,5'S)-hydroxyaverantin + NAD+ | - |
Aspergillus parasiticus NIAH-26 | 5'-oxoaverantin + NADH + H+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
HAVN dehydrogenase | - |
Aspergillus parasiticus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Aspergillus parasiticus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.25 | - |
in 50 mM Tris-HCl buffer (pH 8.5), at 33°C | Aspergillus parasiticus | 4,6-dihydroxy-5-methoxy-6a-methylcyclohexa[de]indano-[7,6-e]cyclopenta[c]2H-pyran-1,9-dione |